Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217203 | 1.00 | KMT2A (0.55) | KMT2AALOX15NPSR1AKR1B1HDAC1 | |
| SCHEMBL9453746 | 0.82 | HDAC1 (0.60) | KMT2AHDAC1HDAC6L3MBTL1MMP2 | |
| Hydrochloric Acid SCHEMBL9225572 | 0.80 | ALOX15 (0.49) | KMT2AALOX15NPSR1HDAC1HDAC6 | |
| SCHEMBL9453685 | 0.80 | KMT2A (0.56) | KMT2AHDAC1HDAC6MMP2MMP1 | |
| SCHEMBL7295633 | 0.79 | ALOX15 (0.40) | KMT2AALOX15NPSR1HDAC1HDAC6 | |
| SCHEMBL9222098 | 0.78 | ALOX15 (0.51) | KMT2AALOX15NPSR1HDAC1HDAC6 | |
| SCHEMBL9453686 | 0.76 | KMT2A (0.51) | KMT2AALOX15NPSR1ALDH1A1KDM4E | |
| SCHEMBL22091733 | 0.74 | KMT2A (0.60) | KMT2AALDH1A1MMP2MMP1MMP9 | |
| SCHEMBL26304198 | 0.74 | KMT2A (0.60) | KMT2AALDH1A1MMP2MMP1MMP9 | |
| SCHEMBL9453601 | 0.73 | HDAC6 (0.53) | KMT2AALOX15HDAC1HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530505-B1 | Hydantoin derivatives | CASSELLA FARBWERKE MAINKUR AG (DE) | 1995-10-11 | — | — | EP | disclosed |
| US-5389614-A | Anticoagulants | CASSELLA AG (DE) | 1995-02-14 | — | — | US | disclosed |
| EP-0530505-A2 | Hydantoin derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-10 | — | — | EP | disclosed |