Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25635649 | 0.78 | ALDH1A1 (0.37) | KDM4E | |
| SCHEMBL12019810 | 0.77 | ALDH1A1 (0.50) | — | |
| SCHEMBL1492543 | 0.77 | ALDH1A1 (0.50) | — | |
| SCHEMBL11507418 | 0.74 | SOAT1 (0.35) | SOAT1KDM4EMAPK1HIF1A | |
| SCHEMBL19014327 | 0.73 | TDP1 (0.41) | — | |
| SCHEMBL5597209 | 0.71 | KDM4E (0.48) | SOAT1KDM4EMAPK1HIF1A | |
| SCHEMBL9073979 | 0.70 | SLC7A5 (0.39) | SOAT1 | |
| SCHEMBL9074201 | 0.68 | SLC7A5 (0.46) | — | |
| SCHEMBL23009650 | 0.68 | — | — | |
| SCHEMBL1902452 | 0.68 | SLC22A6 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509769-B1 | Heterocyclic amides having HLE inhibiting activity | ZENECA LTD (GB) | 1996-09-11 | — | — | EP | disclosed |