Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305728 | 1.00 | CETP (0.52) | CETPALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL27424922 | 1.00 | CETP (0.52) | CETPALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL21245794 | 1.00 | CETP (0.52) | CETPALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL2677628 | 1.00 | CETP (0.52) | CETPALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL3736932 | 1.00 | CETP (0.52) | CETPALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL16648466 | 1.00 | CETP (0.52) | CETPALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL16648564 | 0.98 | ALDH1A1 (0.52) | CETPALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL16648567 | 0.98 | ALDH1A1 (0.52) | CETPALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL30759387 | 0.94 | ALDH1A1 (0.54) | CETPALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL6869938 | 0.94 | ALDH1A1 (0.54) | CETPALDH1A1CYP3A4TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575844-B1 | Hydroxamic acid derivatives and pharmaceutical compositions thereof | HOFFMANN LA ROCHE (CH) | 1998-01-21 | — | — | EP | disclosed |
| EP-0575844-A2 | Hydroxamic acid derivatives and pharmaceutical compositions thereof | F. HOFFMANN-LA ROCHE AG (CH) | 1993-12-29 | — | — | EP | disclosed |