Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 5/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305856 | 1.00 | PREP (0.68) | PREPNPSR1ALDH1A1KDM4ELMNA | |
| SCHEMBL7305097 | 0.93 | PREP (0.68) | PREPNPSR1ALDH1A1KDM4ELMNA | |
| SCHEMBL7305103 | 0.93 | PREP (0.68) | PREPNPSR1ALDH1A1KDM4ELMNA | |
| SCHEMBL7299331 | 0.87 | PREP (0.65) | PREPNPSR1ALDH1A1KDM4ELMNA | |
| SCHEMBL7299336 | 0.87 | PREP (0.65) | PREPNPSR1ALDH1A1KDM4ELMNA | |
| SCHEMBL7297472 | 0.85 | PREP (0.48) | PREPALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL7297465 | 0.85 | PREP (0.48) | PREPALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL7297811 | 0.85 | PREP (0.63) | PREPNPSR1ALDH1A1KDM4ELMNA | |
| SCHEMBL7297805 | 0.85 | PREP (0.63) | PREPNPSR1ALDH1A1KDM4ELMNA | |
| SCHEMBL7305860 | 0.85 | PREP (0.63) | PREPNPSR1ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506256-A | PREVENTION AND/OR TREATMENT OF DEMENTIA, AMNESIA | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0468469-A2 | Proline derivatives | Japan Tobacco Inc. (JP) | 1992-01-29 | — | — | EP | disclosed |