Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.77 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7298240 | 0.98 | SIGMAR1 (0.75) | SIGMAR1ACHECYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL7299989 | 0.98 | SIGMAR1 (0.75) | SIGMAR1ACHECYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL17237763 | 0.98 | SIGMAR1 (0.75) | SIGMAR1ACHECYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL7299921 | 0.87 | SIGMAR1 (1.00) | SIGMAR1ACHECYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL7308430 | 0.87 | SIGMAR1 (0.71) | SIGMAR1ACHECYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL7294524 | 0.87 | SIGMAR1 (0.76) | SIGMAR1ACHECYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL8946216 | 0.85 | SIGMAR1 (0.65) | SIGMAR1ACHECYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL3605597 | 0.85 | SIGMAR1 (0.76) | SIGMAR1CYP11B1CYP11B2ALDH1A1LMNA | |
| SCHEMBL30311216 | 0.83 | SIGMAR1 (0.59) | SIGMAR1ACHECYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL7302267 | 0.83 | SIGMAR1 (0.71) | SIGMAR1ACHECYP11B1CYP11B2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519023-A | SCHIZOPHRENIA | ADIR ET COMPAGNIE (FR) | 1996-05-21 | — | — | US | disclosed |
| EP-0580503-A1 | Aminoalkylchromones, process for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-01-26 | — | — | EP | disclosed |