Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CHKA | P35790 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL388370 | 0.92 | CA2 (0.61) | CA2CHKAMEN1TP53KMT2A | |
| Hydrochloric Acid SCHEMBL1597363 | 0.90 | CA2 (0.59) | CA2CHKAMEN1TP53KMT2A | |
| SCHEMBL3074616 | 0.85 | CA2 (0.64) | CA2CHKAMEN1TP53KMT2A | |
| Hydrochloric Acid SCHEMBL6762954 | 0.83 | CA2 (0.62) | CA2CHKAMEN1TP53KMT2A | |
| Tert-Butyl Formate SCHEMBL27681802 | 0.81 | SMN1; SMN2 (0.44) | CA2CHKAMEN1TP53KMT2A | |
| Trifluoroacetic Acid SCHEMBL9066267 | 0.80 | CA2 (0.48) | CA2CHKAMEN1TP53KMT2A | |
| SCHEMBL10650643 | 0.79 | CA12 (0.46) | CA2CHKAMEN1TP53KMT2A | |
| SCHEMBL2899860 | 0.78 | MEN1 (0.80) | MEN1TP53KMT2ASMN1; SMN2MAPT | |
| SCHEMBL2561632 | 0.78 | CA2 (0.80) | CA2CHKAMEN1TP53KMT2A | |
| SCHEMBL10665698 | 0.76 | CA2 (0.76) | CA2CHKAMEN1TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |