Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20262696 | 0.91 | NPC1 (0.56) | GSK3BHDAC1HDAC8NPC1RAB9A | |
| SCHEMBL846895 | 0.90 | NPC1 (0.65) | GSK3BHDAC8HDAC3HDAC2HDAC6 | |
| SCHEMBL658810 | 0.90 | PDPK1 (0.64) | GSK3BHDAC1POLBNPC1RAB9A | |
| SCHEMBL28668863 | 0.88 | RAB9A (0.71) | GSK3BHDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL241664 | 0.84 | GSK3B (0.70) | GSK3BHDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL8735373 | 0.81 | NPC1 (0.65) | POLBNPC1RAB9AL3MBTL1THRB | |
| SCHEMBL3799020 | 0.81 | NPC1 (0.53) | POLBNPC1RAB9AL3MBTL1THRA | |
| SCHEMBL4484073 | 0.80 | FFAR1 (0.53) | POLBCTDSP1PDPK1FFAR1FFAR4 | |
| SCHEMBL133319 | 0.80 | HDAC1 (0.75) | GSK3BHDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL10766281 | 0.80 | TDP1 (0.77) | HDAC1HDAC8HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8137822-B2 | Synthesis of phenyl-substituted polyfluoroanthenes and the use thereof | BASF AKTIENGESELLSCHAFT (DE) | 2012-03-20 | — | — | US | disclosed |
| US-20080213623-A1 | 7,10-bis(acryloyl, styryl, or glycidyl-substituted phenyl)fluoranthene polymerized in the presence of a nickel or palladium catalyst; photopolymerized after applied to film substrate for organic light-emitting diodes; improved stability, high efficiency and quantum yield, emission maximum in blue region | BASF AKTIENGESELLSCHAFT (DE) | 2008-09-04 | — | — | US | disclosed |