Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.56 |
| ▸ | PREP | P48147 | 11/20 | 0.54 |
| ▸ | ACE | P12821 | 6/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294720 | 0.99 | CHRM2 (0.55) | CHRM2CHRM4CHRM1CHRM3PREP | |
| SCHEMBL7303049 | 0.91 | CHRM2 (0.59) | CHRM2CHRM4CHRM1CHRM3PREP | |
| SCHEMBL7293607 | 0.90 | PREP (0.54) | CHRM2CHRM4CHRM1CHRM3PREP | |
| SCHEMBL7304535 | 0.85 | PREP (0.60) | CHRM2CHRM4CHRM1CHRM3PREP | |
| SCHEMBL7296448 | 0.85 | PREP (0.69) | PREP | |
| SCHEMBL7305422 | 0.83 | PREP (0.74) | CHRM2CHRM4CHRM1CHRM3PREP | |
| SCHEMBL7302790 | 0.83 | PREP (0.51) | PREPACE | |
| SCHEMBL7292436 | 0.82 | PREP (0.57) | PREP | |
| SCHEMBL7297091 | 0.80 | PREP (0.76) | CHRM2CHRM4CHRM1CHRM3PREP | |
| SCHEMBL7302046 | 0.80 | PREP (0.76) | CHRM2CHRM4CHRM1CHRM3PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |