SCHEMBL7302790

SCHEMBL7302790

COC(=O)C1CCCCN1C(=O)CCCCC1Cc2ccccc2C1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PREP P48147 10/20 0.51
LMNA P02545 2/20 0.48
RAB9A P51151 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ACE P12821 1/20 0.46
ALDH1A1 P00352 1/20 0.46
FKBP1A P62942 3/20 0.44
HTR1A P08908 2/20 0.44
HTR7 P34969 2/20 0.44
PKM P14618 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7302358 0.87 FKBP1A (0.48) PREPRAB9AACEFKBP1A
SCHEMBL7296448 0.84 PREP (0.69) PREP
SCHEMBL7305993 0.83 CHRM2 (0.56) PREPACE
SCHEMBL7294720 0.82 CHRM2 (0.55) PREPACEHTR1AHTR7
SCHEMBL7302927 0.82 PREP (0.68) PREPACEALDH1A1
SCHEMBL7293607 0.80 PREP (0.54) PREPACE
SCHEMBL7301169 0.80 PREP (0.70) PREP
SCHEMBL7292436 0.80 PREP (0.57) PREP
SCHEMBL7302982 0.79 PREP (0.54) PREPLMNARAB9ASMN1; SMN2ACE
SCHEMBL7294906 0.79 PREP (0.70) PREPACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed