Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295826 | 0.92 | NPC1 (0.32) | — | |
| SCHEMBL4620956 | 0.92 | NPC1 (0.36) | — | |
| SCHEMBL7302580 | 0.91 | NPC1 (0.39) | — | |
| SCHEMBL7298862 | 0.89 | MEN1 (0.31) | — | |
| SCHEMBL7302728 | 0.89 | OPRM1 (0.38) | — | |
| SCHEMBL7306482 | 0.84 | MEN1 (0.40) | — | |
| SCHEMBL7304360 | 0.83 | FFAR4 (0.33) | — | |
| SCHEMBL7295050 | 0.83 | FFAR4 (0.33) | — | |
| SCHEMBL7304224 | 0.82 | OPRM1 (0.42) | — | |
| SCHEMBL7306774 | 0.82 | OPRM1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135932-A | 2-HYDROXYPROPYLAMINO-ALKYL-BENZIMIDAZOLY-5-YL DERIVATIVES AND THEIR USE IN THE TREATMENT OF HEART DISEASE | DR. KARL THOMAE GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0400519-A1 | 2-Hydroxy-n-propylamines, medicaments containing these compounds and method for preparing them | Dr. Karl Thomae GmbH (DE) | 1990-12-05 | — | — | EP | disclosed |