Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | PLAU | P00749 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 4/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297428 | 0.95 | ITGB3 (0.65) | ITGB3ITGA2BMAPTPLAUTMPRSS2 | |
| SCHEMBL7300012 | 0.95 | ITGB3 (0.59) | ITGB3ITGA2BMAPTPLAUABCB1 | |
| SCHEMBL7310981 | 0.91 | ITGB3 (0.61) | ITGB3ITGA2BMAPTPLAUSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7308159 | 0.90 | ITGB3 (0.60) | ITGB3ITGA2BMAPTPLAUSMN1; SMN2 | |
| SCHEMBL7299808 | 0.89 | ITGB3 (0.67) | ITGB3ITGA2BPLAUTMPRSS2TNF | |
| SCHEMBL7296873 | 0.85 | ITGB3 (0.53) | ITGB3ITGA2BMAPTPLAUSMN1; SMN2 | |
| SCHEMBL7304738 | 0.85 | ITGB3 (0.69) | ITGB3ITGA2BMAPTPLAUSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7311164 | 0.84 | ITGB3 (0.68) | ITGB3ITGA2BMAPTPLAUSMN1; SMN2 | |
| SCHEMBL7307274 | 0.84 | ITGB3 (0.60) | ITGB3ITGA2BPLAUSMN1; SMN2ABCB1 | |
| SCHEMBL7304577 | 0.83 | ITGB3 (0.80) | ITGB3ITGA2BPLAUSMN1; SMN2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |