Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 13/20 | 0.59 |
| ▸ | ACE2 | Q9BYF1 | 6/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297352 | 0.88 | ACE (0.53) | ACEACE2 | |
| SCHEMBL15251959 | 0.87 | ACE (0.64) | ACEACE2KMT2AL3MBTL1 | |
| SCHEMBL15251960 | 0.87 | ACE (0.64) | ACEACE2KMT2AL3MBTL1 | |
| SCHEMBL18619558 | 0.85 | ACE (0.62) | ACEACE2KMT2A | |
| SCHEMBL20485168 | 0.85 | ACE (0.62) | ACEACE2KMT2A | |
| SCHEMBL11284016 | 0.81 | ACE (0.56) | ACEACE2KMT2AL3MBTL1 | |
| SCHEMBL11435575 | 0.80 | ACE (0.71) | ACEACE2TSHR | |
| SCHEMBL3472327 | 0.80 | ACE (0.71) | ACEACE2TSHR | |
| SCHEMBL29749309 | 0.80 | ACE (0.71) | ACEACE2TSHR | |
| SCHEMBL18620607 | 0.80 | ACE (0.57) | ACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494071-B1 | Trifluoromethylketone tripeptide derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-04-16 | — | — | EP | disclosed |
| US-5296591-A | Enzyme inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0494071-A2 | Trifluoromethylketone tripeptide derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |