Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.53 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15251733 | 0.90 | ACE (0.56) | ACEFKBP1AACE2 | |
| SCHEMBL15251734 | 0.90 | ACE (0.56) | ACEFKBP1AACE2 | |
| SCHEMBL7306423 | 0.88 | ACE (0.59) | ACEACE2 | |
| SCHEMBL7297349 | 0.85 | FKBP1A (0.54) | ACEFKBP1AACE2 | |
| SCHEMBL15251803 | 0.81 | ACE (0.59) | ACEFKBP1AACE2 | |
| SCHEMBL15251802 | 0.81 | ACE (0.59) | ACEFKBP1AACE2 | |
| SCHEMBL1992452 | 0.80 | FKBP1A (0.60) | FKBP1A | |
| SCHEMBL18806486 | 0.79 | ACE (0.57) | ACEFKBP1AACE2 | |
| SCHEMBL15251705 | 0.79 | FKBP1A (0.53) | ACEFKBP1A | |
| SCHEMBL15251704 | 0.79 | FKBP1A (0.53) | ACEFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494071-B1 | Trifluoromethylketone tripeptide derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-04-16 | — | — | EP | disclosed |
| US-5296591-A | Enzyme inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0494071-A2 | Trifluoromethylketone tripeptide derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |