Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.59 |
| ▸ | RAB9A | P51151 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 8/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309322 | 0.95 | ITGB3 (0.66) | ITGB3ITGA2BRAB9AMAPTTSHR | |
| SCHEMBL7300485 | 0.94 | ITGB3 (0.67) | ITGB3ITGA2BRAB9AMAPTTSHR | |
| SCHEMBL7300817 | 0.90 | ITGB3 (0.60) | ITGB3ITGA2BRAB9AMAPTTSHR | |
| SCHEMBL7309823 | 0.89 | ITGB3 (0.76) | ITGB3ITGA2BRAB9AMAPTTSHR | |
| SCHEMBL7300011 | 0.88 | ITGB3 (0.64) | ITGB3ITGA2BRAB9AMAPTTSHR | |
| Hydrochloric Acid SCHEMBL7321989 | 0.88 | ITGB3 (0.75) | ITGB3ITGA2BRAB9AMAPTTSHR | |
| SCHEMBL7305310 | 0.86 | ITGB3 (0.78) | ITGB3ITGA2BRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7307505 | 0.86 | ITGB3 (0.49) | ITGB3ITGA2BRAB9AMAPTTSHR | |
| SCHEMBL7303362 | 0.86 | ITGB3 (0.71) | ITGB3ITGA2BRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7303165 | 0.85 | ITGB3 (0.67) | ITGB3ITGA2BRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |