Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2965469 | 0.81 | HTT (0.47) | GAAKDM4EMAPTHTTMEN1 | |
| SCHEMBL17940697 | 0.78 | KDM4E (0.60) | GAAKDM4EMAPTHTTMEN1 | |
| SCHEMBL7297460 | 0.75 | L3MBTL1 (0.49) | GAAKDM4EMAPTHTTMEN1 | |
| SCHEMBL4193660 | 0.73 | GAA (0.54) | GAAKDM4EMAPTHTTMEN1 | |
| SCHEMBL6067901 | 0.73 | KDM4E (0.63) | GAAKDM4EMAPTHTTMEN1 | |
| SCHEMBL14739159 | 0.72 | GAA (0.49) | GAAKDM4EMAPTHTTMEN1 | |
| SCHEMBL17940765 | 0.71 | GAA (1.00) | GAAKDM4EMAPTHTTMEN1 | |
| SCHEMBL20881623 | 0.71 | KDM4E (0.76) | GAAKDM4EMAPTHTTMEN1 | |
| SCHEMBL4188631 | 0.71 | AURKA (0.59) | GAAKDM4EMAPTHTTMEN1 | |
| SCHEMBL21600850 | 0.70 | GAA (0.50) | GAAKDM4EMAPTHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604353-B1 | Benzimidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1998-07-01 | — | — | EP | disclosed |