Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.50 |
| ▸ | F10 | P00742 | 14/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313620 | 0.93 | ITGB3 (0.46) | ITGB3ITGA2BF10SIGMAR1PRSS1 | |
| SCHEMBL6602530 | 0.91 | ITGB3 (0.60) | ITGB3ITGA2BF10SIGMAR1PRSS1 | |
| SCHEMBL7310705 | 0.89 | ITGB3 (0.53) | ITGB3ITGA2BF10SIGMAR1PRSS1 | |
| SCHEMBL7305030 | 0.88 | ITGB3 (0.51) | ITGB3ITGA2BF10SIGMAR1PRSS1 | |
| SCHEMBL7313929 | 0.87 | ITGB3 (0.58) | ITGB3ITGA2BF10SIGMAR1PRSS1 | |
| SCHEMBL6600105 | 0.87 | ITGB3 (0.51) | ITGB3ITGA2BF10SIGMAR1PRSS1 | |
| SCHEMBL7306241 | 0.86 | ITGB3 (0.51) | ITGB3ITGA2BF10SIGMAR1PRSS1 | |
| SCHEMBL7307464 | 0.86 | ITGB3 (0.53) | ITGB3ITGA2BF10SIGMAR1PRSS1 | |
| SCHEMBL7308369 | 0.86 | ITGB3 (0.50) | ITGB3ITGA2BF10SIGMAR1PRSS1 | |
| SCHEMBL7306919 | 0.86 | ITGB3 (0.51) | ITGB3ITGA2BF10SIGMAR1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741133-A2 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-11-06 | — | — | EP | disclosed |