Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 8/20 | 0.60 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 7/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305633 | 1.00 | BACE1 (0.60) | BACE1SLC6A11BCHE | |
| SCHEMBL3352784 | 0.93 | BACE1 (0.54) | BACE1SLC6A11BCHE | |
| SCHEMBL2843607 | 0.93 | BACE1 (0.54) | BACE1SLC6A11BCHE | |
| SCHEMBL2843604 | 0.93 | BACE1 (0.54) | BACE1SLC6A11BCHE | |
| SCHEMBL2188440 | 0.93 | BACE1 (0.54) | BACE1SLC6A11BCHE | |
| SCHEMBL3352792 | 0.93 | BACE1 (0.54) | BACE1SLC6A11BCHE | |
| SCHEMBL3324386 | 0.93 | BACE1 (0.54) | BACE1SLC6A11BCHE | |
| SCHEMBL7610027 | 0.92 | BACE1 (0.71) | BACE1SLC6A11BCHE | |
| SCHEMBL7610032 | 0.92 | BACE1 (0.71) | BACE1SLC6A11BCHE | |
| SCHEMBL5433822 | 0.91 | BACE1 (0.60) | BACE1SLC6A11BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559256-A | Aminediol protease inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0580402-A2 | Aminediol protease inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1994-01-26 | — | — | EP | disclosed |