Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 10/20 | 0.51 |
| ▸ | KDM5A | P29375 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | IPMK | Q8NFU5 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305783 | 0.91 | CYP1B1 (0.52) | CYP1B1CYP1A2ALDH1A1POLBEGFR | |
| SCHEMBL7308871 | 0.90 | CYP1B1 (0.56) | CYP1B1CYP1A2ALDH1A1POLBPPARG | |
| SCHEMBL7303645 | 0.90 | CYP1B1 (0.57) | CYP1B1CYP1A2ALDH1A1POLBCYP3A4 | |
| SCHEMBL7316873 | 0.90 | CYP1B1 (0.57) | CYP1B1CYP1A2ALDH1A1POLBEGFR | |
| SCHEMBL7311118 | 0.90 | CYP1B1 (0.57) | CYP1B1CYP1A2ALDH1A1POLBCYP3A4 | |
| SCHEMBL4393314 | 0.90 | CYP1B1 (0.67) | CYP1B1CYP1A2KDM4EALDH1A1POLB | |
| SCHEMBL7304788 | 0.89 | MAPT (0.63) | CYP1B1CYP1A2ALDH1A1POLBCYP2C9 | |
| SCHEMBL7307391 | 0.89 | CYP1B1 (0.53) | CYP1B1CYP1A2ALDH1A1POLBEGFR | |
| SCHEMBL7310036 | 0.89 | CYP1B1 (0.55) | CYP1B1CYP1A2ALDH1A1POLBEGFR | |
| SCHEMBL10472448 | 0.89 | CYP1A2 (0.63) | CYP1B1CYP1A2KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832886-B1 | Flavon derivatives, process for their preparation, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-11-13 | — | — | EP | claimed |
| US-5889003-A | PHOSPHODIESTERASE INHIBITOR | ADIR ET COMPAGNIE (FR) | 1999-03-30 | — | — | US | claimed |
| EP-0832886-A1 | Flavon derivatives, process for their preparation, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-01 | — | — | EP | claimed |
| EP-0832886-B1 | Flavon derivatives, process for their preparation, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-11-13 | — | — | EP | disclosed |
| EP-0832886-A1 | Flavon derivatives, process for their preparation, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-01 | — | — | EP | disclosed |