Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 1/20 | 0.61 |
| ▸ | KDM5A | P29375 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 10/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.58 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.58 |
| ▸ | KDM1A | O60341 | 1/20 | 0.58 |
| ▸ | XDH | P47989 | 1/20 | 0.58 |
| ▸ | IPMK | Q8NFU5 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10472448 | 0.97 | CYP1A2 (0.63) | CYP1B1CYP1A2ALDH1A1POLBKDM4E | |
| SCHEMBL8429583 | 0.94 | CYP1B1 (0.67) | CYP1B1CYP1A2ALDH1A1POLBKDM4E | |
| SCHEMBL8429540 | 0.94 | EGFR (0.59) | CYP1B1CYP1A2ALDH1A1POLBKDM4E | |
| SCHEMBL4397722 | 0.92 | KDM4E (0.70) | CYP1B1CYP1A2ALDH1A1POLBKDM4E | |
| SCHEMBL10473384 | 0.91 | CYP1B1 (0.72) | CYP1B1CYP1A2ALDH1A1POLBKDM4E | |
| SCHEMBL8429585 | 0.91 | CYP1B1 (0.56) | CYP1B1CYP1A2ALDH1A1POLBKDM4E | |
| SCHEMBL14178914 | 0.91 | CYP1B1 (0.71) | CYP1B1CYP1A2ALDH1A1POLBCYP3A4 | |
| SCHEMBL8431160 | 0.90 | ALDH1A1 (0.56) | CYP1B1CYP1A2ALDH1A1POLBKDM4E | |
| SCHEMBL7306885 | 0.90 | CYP1B1 (0.54) | CYP1B1CYP1A2ALDH1A1POLBKDM4E | |
| SCHEMBL8427276 | 0.89 | CYP1B1 (0.56) | CYP1B1CYP1A2ALDH1A1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660074-B1 | 7-CARBOXYMETHYLOXY-3 , 4 , 5-TRIMETHOXY FLAVONE MONOHYD RATE, THE PREPARATION METHOD AND USES THEREOF | DONG A PHARM CO LTD (KR) | 2009-12-16 | — | — | EP | disclosed |
| EP-2065375-A1 | A process for the preparation of 7-carboxymethyloxy-3',4', 5-trimethoxy flavone | Dong-A Pharmaceutical Co., Ltd. (KR) | 2009-06-03 | — | — | EP | disclosed |
| US-7371775-B2 | 7-carboxymethyloxy-3′,4′,5-trimethoxy flavone monohydrate, the preparation method and uses thereof | DONG-A PHARMACEUTICALS CO., LTD (KR) | 2008-05-13 | — | — | US | disclosed |
| US-20060178428-A1 | 7-Carboxymethyloxy-3',4',5-trimethoxy flavone monohydrate, the preparation method and uses thereof | DONG-A PHARMACEUTICAL CO., LTD (KR) | 2006-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178428-A1 | 7-Carboxymethyloxy-3',4',5-trimethoxy flavone monohydrate, the preparation method and uses thereof | SI, MLN, TET2 | CYP1B1 680/4885CYP1A2 233/4885ALDH1A1 1642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.