Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 3/20 | 0.56 |
| ▸ | CPA2 | P48052 | 3/20 | 0.56 |
| ▸ | CPA4 | Q9UI42 | 3/20 | 0.56 |
| ▸ | CPB1 | P15086 | 1/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | REN | P00797 | 3/20 | 0.53 |
| ▸ | PAM | P19021 | 1/20 | 0.52 |
| ▸ | MME | P08473 | 2/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.49 |
| ▸ | GNPAT | O15228 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306969 | 1.00 | CPA1 (0.56) | CPA1CPA2CPA4CPB1ACE2 | |
| SCHEMBL7305024 | 0.86 | PSMB5 (0.53) | RENMMEPSMB5 | |
| SCHEMBL7305034 | 0.86 | PSMB5 (0.53) | RENMMEPSMB5 | |
| SCHEMBL7306858 | 0.85 | CAPN1 (0.67) | — | |
| SCHEMBL7306872 | 0.85 | CAPN1 (0.67) | — | |
| SCHEMBL30777486 | 0.85 | MME (0.65) | CPA1CPA2CPA4CPB1ACE2 | |
| SCHEMBL15692334 | 0.85 | MME (0.65) | CPA1CPA2CPA4CPB1ACE2 | |
| SCHEMBL17210510 | 0.85 | BACE1 (0.50) | CPA1CPA2CPA4CPB1ACE2 | |
| SCHEMBL7311952 | 0.85 | REN (0.67) | REN | |
| SCHEMBL7311940 | 0.85 | REN (0.67) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525420-B1 | Pseudopeptides and dipeptides characterised by a substituted methyl ketone moiety at the C-terminus as thiol protease inhibitors | MITSUBISHI CHEM CORP (JP) | 1999-05-12 | — | — | EP | disclosed |
| US-5834508-A | PROTEASE ENZYME INHIBITORS; MUSCLE DISORDERS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |
| US-5639783-A | POTENT PROTEASE INHIBITOR FOR TREATING MUSCULAR, NERVOUS SYSTEM DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0525420-A1 | Pseudopeptides and dipeptides characterised by a substituted methyl ketone moiety at the C-terminus as thiol protease inhibitors | Mitsubishi Chemical Corporation (JP) | 1993-02-03 | — | — | EP | disclosed |