Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.56 |
| ▸ | F10 | P00742 | 4/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.39 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299155 | 0.87 | ITGB3 (0.75) | ITGB3ITGA2BMCHR1 | |
| SCHEMBL7305419 | 0.86 | ITGB3 (0.74) | ITGB3ITGA2BF10PRSS1F2 | |
| Hydrochloric Acid SCHEMBL7315353 | 0.86 | ITGB3 (0.74) | ITGB3ITGA2BMCHR1 | |
| SCHEMBL7308742 | 0.85 | ITGB3 (0.66) | ITGB3ITGA2BF10PRSS1F2 | |
| SCHEMBL7305927 | 0.82 | ITGB3 (0.63) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| SCHEMBL7302786 | 0.80 | ITGB3 (0.65) | ITGB3ITGA2BMCHR1 | |
| SCHEMBL7311321 | 0.80 | ITGB3 (0.50) | ITGB3ITGA2BF10F2 | |
| SCHEMBL7301374 | 0.80 | ITGB3 (0.50) | ITGB3ITGA2BF10F2 | |
| SCHEMBL7303456 | 0.80 | ITGB3 (0.72) | ITGB3ITGA2BMCHR1 | |
| SCHEMBL7298689 | 0.79 | ITGB3 (0.58) | ITGB3ITGA2BMCHR1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |