Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 7/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7300230 | 0.99 | FGFR1 (0.57) | FGFR1HTTKDM4EALDH1A1RAB9A | |
| SCHEMBL7167684 | 0.87 | NOS2 (0.53) | HTTKDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL3417304 | 0.83 | HTT (0.78) | FGFR1HTT | |
| SCHEMBL7295761 | 0.80 | NOS2 (0.46) | HTTKDM4ERAB9ASMN1; SMN2ROCK1 | |
| SCHEMBL17993391 | 0.80 | FGFR1 (0.63) | FGFR1HTTKDM4E | |
| SCHEMBL7165172 | 0.79 | NOS2 (0.49) | HTTKDM4ERAB9ASMN1; SMN2ROCK1 | |
| SCHEMBL2306019 | 0.79 | FGFR1 (0.67) | FGFR1HTTKDM4EALDH1A1RAB9A | |
| SCHEMBL2309144 | 0.77 | MAPK1 (0.61) | HTTALDH1A1RAB9ASMN1; SMN2ROCK1 | |
| SCHEMBL23652406 | 0.77 | KDM4E (0.55) | HTTKDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL13052913 | 0.77 | HTT (0.77) | FGFR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604353-B1 | Benzimidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1998-07-01 | — | — | EP | claimed |