Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159894 | 0.92 | ACACB (0.43) | MAPTGAAPKMMGLLACACB | |
| Hydrochloric Acid SCHEMBL14775596 | 0.91 | ACACB (0.42) | MAPTGAAPKMMGLLACACB | |
| SCHEMBL25240714 | 0.83 | SMN1; SMN2 (0.42) | MAPTGAAPKMMGLLMEN1 | |
| SCHEMBL3707018 | 0.82 | ACACB (0.43) | MAPTACACBACACAESR1MEN1 | |
| SCHEMBL8632170 | 0.79 | MAPT (0.64) | MAPTGAAPKMKMT2AL3MBTL1 | |
| SCHEMBL6170448 | 0.78 | KDM4E (0.45) | GAAATML3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL158112 | 0.78 | ACACB (0.45) | ACACBACACAKMT2AMAPK1KDM4E | |
| SCHEMBL14855501 | 0.77 | ACACB (0.43) | ACACBACACAKMT2ACYP1A2KDM4E | |
| SCHEMBL28048356 | 0.76 | ACACB (0.44) | MAPTACACBACACAKMT2AGPR84 | |
| SCHEMBL8848140 | 0.76 | ACACB (0.44) | ACACBACACAKMT2ACYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502314-B1 | Benzimidazol derivatives, medicaments containing them and process for their preparation | THOMAE GMBH DR K (DE) | 1998-05-20 | — | — | EP | disclosed |
| EP-0502314-A1 | Benzimidazol, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-09 | — | — | EP | disclosed |