Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.59 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310560 | 0.95 | AGTR1 (0.59) | PPARGAGTR1AGTR2 | |
| SCHEMBL7311537 | 0.89 | AGTR1 (0.60) | PPARGAGTR1AGTR2 | |
| SCHEMBL7307386 | 0.88 | PPARG (0.76) | PPARGAGTR1AGTR2 | |
| SCHEMBL7309147 | 0.88 | PPARG (0.60) | PPARG | |
| SCHEMBL9041506 | 0.87 | PPARG (0.73) | PPARGAGTR1AGTR2 | |
| SCHEMBL8790051 | 0.86 | PPARG (0.57) | PPARGAGTR1 | |
| SCHEMBL9042831 | 0.86 | PPARG (0.74) | PPARG | |
| SCHEMBL8788417 | 0.85 | PPARG (0.64) | PPARGAGTR1AGTR2 | |
| SCHEMBL7310465 | 0.84 | PPARG (0.56) | PPARG | |
| SCHEMBL8788054 | 0.84 | PPARG (0.55) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502314-A1 | Benzimidazol, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-09 | — | — | EP | disclosed |