SCHEMBL7307432

SCHEMBL7307432

CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KLK7 P49862 1/20 0.61
FKBP1A P62942 9/20 0.60
PREP P48147 5/20 0.59
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
HSD17B10 Q99714 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9609458 1.00 KLK7 (0.61) KLK7FKBP1APREPMEN1KMT2A
SCHEMBL9610764 1.00 KLK7 (0.61) KLK7FKBP1APREPMEN1KMT2A
SCHEMBL6925800 0.98 FKBP1A (0.64) KLK7FKBP1APREPMEN1KMT2A
SCHEMBL159105 0.96 KLK7 (0.66) KLK7FKBP1APREPMEN1KMT2A
SCHEMBL5970730 0.96 KLK7 (0.66) KLK7FKBP1APREPMEN1KMT2A
SCHEMBL159104 0.96 KLK7 (0.66) KLK7FKBP1APREPMEN1KMT2A
SCHEMBL13257218 0.92 FKBP1A (0.70) KLK7FKBP1APREPMEN1KMT2A
SCHEMBL16531226 0.92 FKBP1A (0.70) KLK7FKBP1APREPMEN1KMT2A
SCHEMBL221644 0.92 FKBP1A (0.70) KLK7FKBP1APREPMEN1KMT2A
SCHEMBL10522061 0.91 PREP (0.64) KLK7FKBP1APREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118684727-A GPRP series peptide modified dabigatran derivative, synthesis, activity and application thereof 首都医科大学 2024-09-24 CN claimed
CN-118684727-A GPRP series peptide modified dabigatran derivative, synthesis, activity and application thereof 首都医科大学 2024-09-24 CN disclosed
US-5506256-A PREVENTION AND/OR TREATMENT OF DEMENTIA, AMNESIA YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1996-04-09 US disclosed
EP-0468469-A2 Proline derivatives Japan Tobacco Inc. (JP) 1992-01-29 EP disclosed
US-4971993-A HYPOTENSIVE DIPEPTIDES DERIVATIVES AJINOMOTO CO., INC. (JP) 1990-11-20 US disclosed
EP-0190852-A2 Dipeptide derivatives and antihypertensive drugs containing them AJINOMOTO CO., INC. (JP) 1986-08-13 EP disclosed