Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CLK1 | P49759 | 2/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | PDE9A | O76083 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28869476 | 0.82 | CLK1 (0.49) | CA1CA2CLK1DYRK1ANCOA3 | |
| SCHEMBL31457372 | 0.82 | CLK1 (0.49) | CA1CA2CLK1DYRK1ANCOA3 | |
| SCHEMBL7302966 | 0.79 | CA1 (0.41) | CA1CA2IMPDH2IMPDH1 | |
| SCHEMBL8955230 | 0.78 | DYRK1A (0.45) | CA1CA2CLK1DYRK1ANCOA3 | |
| SCHEMBL10829252 | 0.78 | CLK1 (0.45) | CA1CA2CLK1DYRK1ANCOA3 | |
| SCHEMBL9453843 | 0.78 | CLK1 (0.45) | CA1CA2CLK1DYRK1ANCOA3 | |
| SCHEMBL3961346 | 0.78 | DYRK1A (0.45) | CA1CA2CLK1DYRK1ANCOA3 | |
| SCHEMBL11845987 | 0.78 | KDM4E (0.47) | CA1CA2CLK1DYRK1ANCOA3 | |
| SCHEMBL10338293 | 0.78 | KDM4E (0.59) | CA1CA2CLK1DYRK1ANCOA3 | |
| SCHEMBL27541400 | 0.76 | KDM4E (0.58) | CA1CA2CLK1DYRK1ANCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |