Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.33 |
| ▸ | MIF | P14174 | 2/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307452 | 0.79 | CA1 (0.46) | CA1CA2IMPDH2IMPDH1 | |
| SCHEMBL5249907 | 0.76 | IMPDH2 (0.37) | CA1CA2IMPDH2IMPDH1CYP2A6 | |
| SCHEMBL6397705 | 0.76 | IMPDH2 (0.37) | CA1CA2IMPDH2IMPDH1CYP2A6 | |
| SCHEMBL29420450 | 0.74 | IMPDH2 (0.47) | CA1CA2IMPDH2IMPDH1CYP2A6 | |
| SCHEMBL8852599 | 0.74 | IMPDH2 (0.47) | CA1CA2IMPDH2IMPDH1CYP2A6 | |
| SCHEMBL28274538 | 0.69 | IMPDH2 (0.50) | CA1CA2IMPDH2IMPDH1CYP2A6 | |
| SCHEMBL13037656 | 0.68 | CA2 (0.55) | CA1CA2IMPDH2IMPDH1CYP2A6 | |
| SCHEMBL818900 | 0.67 | CA1 (0.55) | CA1CA2IMPDH2IMPDH1CYP2A6 | |
| SCHEMBL29489126 | 0.67 | CA1 (0.55) | CA1CA2IMPDH2IMPDH1CYP2A6 | |
| SCHEMBL3027684 | 0.66 | IMPDH2 (0.42) | CA1CA2IMPDH2IMPDH1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |