Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10829572 | 0.86 | PSMB5 (0.51) | PSMB5SMN1; SMN2GAAALOX15CTSD | |
| SCHEMBL10829697 | 0.81 | PSMB5 (0.47) | PSMB5SMN1; SMN2SLC7A5CTSDMAPK1 | |
| SCHEMBL30085015 | 0.78 | SLC7A5 (0.47) | PSMB5SLC7A5TSHREPHX1DPP4 | |
| Hydrochloric Acid SCHEMBL11168293 | 0.77 | PRCP (0.38) | SLC7A5TSHRDPP4DPP8DPP9 | |
| SCHEMBL7307570 | 0.77 | EPHX1 (0.56) | SMN1; SMN2GAATSHRMEN1KMT2A | |
| SCHEMBL5752738 | 0.76 | PRCP (0.43) | SLC7A5DPP4DPP8DPP9DPP7 | |
| SCHEMBL5751421 | 0.76 | PRCP (0.43) | SLC7A5DPP4DPP8DPP9DPP7 | |
| SCHEMBL10377188 | 0.76 | TSHR (0.43) | SMN1; SMN2CTSDMAPK1TSHRMEN1 | |
| SCHEMBL25468260 | 0.75 | HDAC8 (0.44) | SMN1; SMN2HDAC8HDAC6GAATSHR | |
| SCHEMBL13995144 | 0.75 | EPHX1 (0.53) | SMN1; SMN2GAASLC7A5TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5214056-A | Thiol protease inhibitors | JAPAN TOBACCO INC. (JP) | 1993-05-25 | — | — | US | disclosed |
| EP-0460239-A1 | 1,3,2-DIOXATHIOLANE OXIDE DERIVATIVE | Japan Tobacco Inc. (JP) | 1991-12-11 | — | — | EP | disclosed |