Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ARG1 | P05089 | 2/20 | 0.44 |
| ▸ | ARG2 | P78540 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13995144 | 0.98 | EPHX1 (0.53) | EPHX1ATMMEN1TSHRKMT2A | |
| SCHEMBL7375831 | 0.95 | EPHX1 (0.49) | EPHX1ATMMEN1TSHRKMT2A | |
| SCHEMBL7375829 | 0.95 | EPHX1 (0.49) | EPHX1ATMMEN1TSHRKMT2A | |
| SCHEMBL7373390 | 0.91 | SLC7A5 (0.47) | EPHX1KMT2ARAB9ASMN1; SMN2GAA | |
| SCHEMBL7373388 | 0.91 | SLC7A5 (0.47) | EPHX1KMT2ARAB9ASMN1; SMN2GAA | |
| SCHEMBL4078143 | 0.85 | ARG1 (0.47) | EPHX1MEN1TSHRKMT2ARAB9A | |
| SCHEMBL17152290 | 0.83 | ARG1 (0.42) | EPHX1MEN1TSHRKMT2AARG1 | |
| SCHEMBL17152645 | 0.83 | CCR1 (0.55) | EPHX1SMN1; SMN2GAAKDM4E | |
| SCHEMBL21671294 | 0.83 | CTSK (0.43) | EPHX1ATMMEN1TSHRKMT2A | |
| SCHEMBL21671135 | 0.83 | CTSK (0.43) | EPHX1ATMMEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5214056-A | Thiol protease inhibitors | JAPAN TOBACCO INC. (JP) | 1993-05-25 | — | — | US | disclosed |
| EP-0460239-A1 | 1,3,2-DIOXATHIOLANE OXIDE DERIVATIVE | Japan Tobacco Inc. (JP) | 1991-12-11 | — | — | EP | disclosed |