Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2296442 | 0.79 | — | — | |
| SCHEMBL11430568 | 0.79 | FFAR3 (0.36) | PYGM | |
| SCHEMBL232172 | 0.69 | TPMT (0.32) | PYGM | |
| SCHEMBL9255427 | 0.66 | TDP1 (0.32) | — | |
| SCHEMBL168735 | 0.65 | PYGM (0.35) | PYGM | |
| SCHEMBL1428318 | 0.65 | PYGM (0.35) | PYGM | |
| SCHEMBL1286030 | 0.65 | PYGM (0.35) | PYGM | |
| SCHEMBL4759595 | 0.65 | PYGM (0.31) | PYGM | |
| SCHEMBL350922 | 0.65 | — | — | |
| SCHEMBL30770833 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454121-B1 | Azatetracyclic compounds | SEARLE & CO (US) | 1996-11-13 | — | — | EP | claimed |
| US-5223613-A | Prepared from cyclopenta(c)pyrrole derivatives; drug intermediates; antiemetics, anixiolytics | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | claimed |
| EP-0454121-A2 | Azatetracyclic compounds | G.D. Searle & Co. (US) | 1991-10-30 | — | — | EP | claimed |