Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.79 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.79 |
| ▸ | TMPRSS2 | O15393 | 6/20 | 0.53 |
| ▸ | PLAU | P00749 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307122 | 0.95 | ITGB3 (0.70) | ITGB3ITGA2BTMPRSS2PLAUKDM4E | |
| SCHEMBL7305449 | 0.93 | ITGB3 (0.92) | ITGB3ITGA2BTMPRSS2PLAU | |
| Hydrochloric Acid SCHEMBL7320907 | 0.92 | ITGB3 (0.90) | ITGB3ITGA2BTMPRSS2PLAU | |
| SCHEMBL7304577 | 0.88 | ITGB3 (0.80) | ITGB3ITGA2BTMPRSS2PLAUKDM4E | |
| SCHEMBL7297076 | 0.86 | ITGB3 (0.60) | ITGB3ITGA2BTMPRSS2PLAUKDM4E | |
| SCHEMBL7301277 | 0.86 | ITGB3 (0.70) | ITGB3ITGA2BPLAUKDM4ESMN1; SMN2 | |
| SCHEMBL7397281 | 0.85 | ITGB3 (0.68) | ITGB3ITGA2BTMPRSS2PLAUKDM4E | |
| SCHEMBL7435004 | 0.84 | ITGB3 (0.67) | ITGB3ITGA2BTMPRSS2PLAUKDM4E | |
| SCHEMBL7396832 | 0.83 | ITGB3 (0.66) | ITGB3ITGA2BTMPRSS2PLAUKDM4E | |
| SCHEMBL7392173 | 0.83 | ITGB3 (0.66) | ITGB3ITGA2BTMPRSS2PLAUKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |