Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7039447 | 0.89 | CCR1 (0.54) | HTR1D | |
| SCHEMBL7038210 | 0.88 | — | — | |
| SCHEMBL7299616 | 0.86 | HTR1D (0.66) | HTR1D | |
| SCHEMBL7305248 | 0.84 | HTR1D (0.57) | HTR1D | |
| SCHEMBL7035190 | 0.84 | HTR1D (0.76) | HTR1D | |
| SCHEMBL7038215 | 0.82 | HTR1D (0.54) | HTR1D | |
| SCHEMBL7310103 | 0.77 | OPRL1 (0.61) | HTR1D | |
| SCHEMBL7040978 | 0.77 | OPRL1 (0.52) | HTR1D | |
| SCHEMBL16226753 | 0.77 | ALDH1A1 (0.66) | — | |
| SCHEMBL9036819 | 0.77 | HTR1D (0.69) | HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153611-A | AS NON-DOPAMINERGIC ANTIISCHEMIC COMPOUNDS FOR TREATING BRAIN DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-11-28 | — | — | US | disclosed |
| EP-0560669-B1 | Piperazinyl-and piperidinyl-cyclohexenes and cyclohexanes | BRISTOL MYERS SQUIBB CO (US) | 1995-06-14 | — | — | EP | disclosed |
| EP-0560669-A1 | Piperazinyl-and piperidinyl-cyclohexenes and cyclohexanes | Bristol-Myers Squibb Company (US) | 1993-09-15 | — | — | EP | disclosed |