Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 6/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11189804 | 1.00 | TRHR (0.53) | TRHR | |
| SCHEMBL4957292 | 1.00 | TRHR (0.53) | TRHR | |
| Citric Acid SCHEMBL11188973 | 0.92 | TRHR (0.46) | TRHR | |
| Citric Acid SCHEMBL3095494 | 0.92 | TRHR (0.46) | TRHR | |
| SCHEMBL8256990 | 0.88 | TRHR (0.40) | TRHR | |
| SCHEMBL14028670 | 0.88 | TRHR (0.41) | TRHR | |
| SCHEMBL7327392 | 0.85 | TRHR (0.51) | TRHR | |
| SCHEMBL7334673 | 0.84 | TRHR (0.51) | TRHR | |
| Azetirelin SCHEMBL10703548 | 0.84 | TRHR (0.62) | TRHR | |
| Azetirelin SCHEMBL7265691 | 0.84 | TRHR (0.62) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067513-B1 | PHARMACEUTICAL PREPARATIONS CONTAINING TRH OR ITS ANALOGUE | Takeda Chemical Industries, Ltd. (JP) | 1987-07-15 | — | — | EP | claimed |
| US-4659696-A | MIXTURE OF POLYPEPTIDE AND CYCLODEXTRIN | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-04-21 | — | — | US | claimed |
| US-4504470-A | THYROTROPIN RELEASING HORMONE, CARBOXY ACID, DOSAGE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-03-12 | — | — | US | claimed |
| EP-0067513-A2 | Pharmaceutical preparations containing TRH or its analogue | Takeda Chemical Industries, Ltd. (JP) | 1982-12-22 | — | — | EP | claimed |
| US-4100152-A | Peptides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1978-07-11 | — | — | US | claimed |
| JP-59216825-A | — | — | None | — | — | JP | disclosed |
| US-4665056-A | CENTRAL NERVOUS SYSTEM DISORDERS | TANABE SEIYAKU CO., LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| EP-0168042-A2 | Dihydroorotic acid derivatives, processes for their preparing and pharmaceutical composition containing them | TANABE SEIYAKU CO., LTD. (JP) | 1986-01-15 | — | — | EP | disclosed |
| US-4504470-A | THYROTROPIN RELEASING HORMONE, CARBOXY ACID, DOSAGE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-03-12 | — | — | US | disclosed |
| JP-S59216825-A | EXTERNAL DRUG FOR TRANSCUTANEOUS ABSORPTION | TAKEDA CHEM IND LTD | 1984-12-06 | — | — | JP | disclosed |
| US-4442090-A | ACYLATED AMINO ACID | KYOTO YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 1984-04-10 | — | — | US | disclosed |
| US-4421745-A | PEPTIDE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-12-20 | — | — | US | disclosed |