Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314206 | 1.00 | EBP (0.43) | EBPSIGMAR1L3MBTL1CYP3A4ADRA1D | |
| SCHEMBL7318454 | 0.93 | EBP (0.43) | EBPSIGMAR1L3MBTL1CYP3A4ADRA1D | |
| SCHEMBL7305253 | 0.91 | EBP (0.41) | EBPSIGMAR1L3MBTL1CYP3A4NAAA | |
| SCHEMBL7304195 | 0.91 | EBP (0.41) | EBPSIGMAR1L3MBTL1CYP3A4NAAA | |
| SCHEMBL7309770 | 0.90 | EBP (0.44) | EBPSIGMAR1L3MBTL1CYP3A4ADRA1D | |
| SCHEMBL7305541 | 0.88 | EBP (0.43) | EBPSIGMAR1L3MBTL1CYP3A4ADRA1D | |
| SCHEMBL7306594 | 0.88 | EBP (0.43) | EBPSIGMAR1L3MBTL1CYP3A4ADRA1D | |
| SCHEMBL7315152 | 0.88 | EBP (0.39) | EBPSIGMAR1L3MBTL1CYP3A4ADRA1D | |
| SCHEMBL7304422 | 0.87 | CTSL (0.50) | EBPSIGMAR1CTSLCTSSCTSK | |
| SCHEMBL7303551 | 0.85 | EBP (0.48) | EBPSIGMAR1L3MBTL1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |