Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 19/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6422995 | 0.95 | TACR2 (0.58) | TACR2 | |
| SCHEMBL8368093 | 0.83 | TACR2 (0.44) | TACR2 | |
| SCHEMBL7305547 | 0.83 | MEN1 (0.43) | TACR2 | |
| SCHEMBL8971656 | 0.83 | TACR2 (0.45) | TACR2 | |
| SCHEMBL8971591 | 0.82 | TACR2 (0.47) | TACR2 | |
| SCHEMBL9318295 | 0.82 | TACR2 (0.45) | TACR2 | |
| SCHEMBL8695178 | 0.81 | TACR2 (0.43) | TACR2 | |
| SCHEMBL8479637 | 0.80 | TACR2 (0.43) | TACR2 | |
| SCHEMBL7306485 | 0.79 | SLC6A3 (0.45) | TACR2 | |
| SCHEMBL8971567 | 0.79 | TACR2 (0.42) | TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294537-B1 | NEUROKININS USED FOR TREATMENT OF DISEASES | SANOFI-SYNTHELABO (FR) | 2001-09-25 | — | — | US | disclosed |
| US-6124316-A | ACTIVE DRUG TREATING PSYCHIATRIC DISEASES, DISEASES OF PSYCHOSOMATIC ORIGIN, OF HYPERTENSION AND, NERVOUS SYSTEM DISORDERS | SANOFI (FR) | 2000-09-26 | — | — | US | disclosed |
| EP-0673928-A1 | Novel N-(3,4-dichlorophenyl-propyl)-piperidine derivatives as selective human NK3-receptor antagonists | SANOFI (FR) | 1995-09-27 | — | — | EP | disclosed |