Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 14/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 14/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 14/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 14/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307685 | 0.89 | PPIA (0.37) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7311966 | 0.89 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7319316 | 0.89 | PDE3B (0.37) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7320078 | 0.87 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7316546 | 0.85 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7318132 | 0.79 | NPC1 (0.38) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7303658 | 0.79 | PDE3B (0.39) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7314402 | 0.79 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7310955 | 0.79 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7309755 | 0.78 | PDE3B (0.36) | PDE4APDE4BPDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739056-A | ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-04-19 | — | — | US | disclosed |