Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 8/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311966 | 0.90 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7307685 | 0.88 | PPIA (0.37) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7307830 | 0.87 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7316546 | 0.84 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7316080 | 0.83 | PDE3B (0.36) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7313053 | 0.82 | PDE3B (0.38) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7309755 | 0.80 | PDE3B (0.36) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7314566 | 0.80 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7311053 | 0.80 | PDE3B (0.36) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7314037 | 0.77 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739056-A | ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-04-19 | — | — | US | disclosed |