Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4984205 | 0.94 | TACR2 (0.62) | TACR2TACR1 | |
| SCHEMBL6425161 | 0.84 | TACR2 (0.65) | TACR2TACR1 | |
| SCHEMBL7313105 | 0.84 | TACR2 (0.67) | TACR2TACR1 | |
| SCHEMBL6609213 | 0.84 | TACR2 (0.62) | TACR2TACR1 | |
| SCHEMBL9318213 | 0.83 | TACR2 (0.47) | TACR2TACR1 | |
| SCHEMBL7306571 | 0.82 | TACR2 (0.40) | TACR2TACR1 | |
| SCHEMBL8315120 | 0.82 | TACR2 (0.49) | TACR2TACR1 | |
| SCHEMBL4873822 | 0.82 | TACR2 (0.70) | TACR2TACR1 | |
| SCHEMBL4610521 | 0.82 | TACR2 (0.70) | TACR2TACR1 | |
| SCHEMBL14263854 | 0.82 | TACR2 (0.70) | TACR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294537-B1 | NEUROKININS USED FOR TREATMENT OF DISEASES | SANOFI-SYNTHELABO (FR) | 2001-09-25 | — | — | US | disclosed |
| US-6124316-A | ACTIVE DRUG TREATING PSYCHIATRIC DISEASES, DISEASES OF PSYCHOSOMATIC ORIGIN, OF HYPERTENSION AND, NERVOUS SYSTEM DISORDERS | SANOFI (FR) | 2000-09-26 | — | — | US | disclosed |
| US-5942523-A | NOVEL PIPERIDINE DERIVATIVES WHOSE SPECIFIC STRUCTURE INCLUDES AT POSITION 1 AN ALKYL CHAIN HAVING A 3,4-DICHLOROPHENYL GROUP ATTACHED; HIGH SELECTIVITY TO THE NK3 RECEPTOR; UNIT DOSAGE FORM; TREATING PSYCHIATRIC DISEASES | SANOFI (FR) | 1999-08-24 | — | — | US | disclosed |
| US-5741910-A | PIPERIDINE DERIVATIVE INTERMEDIATES | SANOFI (FR) | 1998-04-21 | — | — | US | disclosed |
| EP-0673928-A1 | Novel N-(3,4-dichlorophenyl-propyl)-piperidine derivatives as selective human NK3-receptor antagonists | SANOFI (FR) | 1995-09-27 | — | — | EP | disclosed |