Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | F2R | P25116 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ITGAL | P20701 | 2/20 | 0.48 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.48 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307943 | 1.00 | MAPT (0.67) | MAPTL3MBTL1POLBALDH1A1F2R | |
| SCHEMBL7309304 | 0.96 | MAPT (0.66) | MAPTL3MBTL1POLBALDH1A1F2R | |
| SCHEMBL7309311 | 0.96 | MAPT (0.66) | MAPTL3MBTL1POLBALDH1A1F2R | |
| SCHEMBL7307640 | 0.92 | MAPT (0.63) | MAPTL3MBTL1POLBF2RLMNA | |
| SCHEMBL7307644 | 0.92 | MAPT (0.63) | MAPTL3MBTL1POLBF2RLMNA | |
| SCHEMBL7303644 | 0.90 | L3MBTL1 (0.71) | MAPTL3MBTL1POLBALDH1A1F2R | |
| SCHEMBL7303641 | 0.90 | L3MBTL1 (0.71) | MAPTL3MBTL1POLBALDH1A1F2R | |
| SCHEMBL7313986 | 0.84 | MAPT (0.70) | MAPTL3MBTL1POLBF2RLMNA | |
| SCHEMBL7313994 | 0.84 | MAPT (0.70) | MAPTL3MBTL1POLBF2RLMNA | |
| SCHEMBL7306010 | 0.81 | HTT (0.70) | MAPTL3MBTL1ALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |