SCHEMBL7308091

SCHEMBL7308091

C[C@]12CCC(=O)C[C@@]1(O)CCC2=O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29116326 1.00 LMNA (0.31) LMNACYP2C9
SCHEMBL11458377 1.00 LMNA (0.31) LMNACYP2C9
SCHEMBL11465057 1.00 LMNA (0.31) LMNACYP2C9
SCHEMBL24483622 0.74 LMNA (0.34) LMNACYP2C9
SCHEMBL13564562 0.72 LMNA (0.31) LMNACYP2C9
SCHEMBL11607768 0.72
SCHEMBL11607759 0.72
SCHEMBL22930634 0.69
SCHEMBL14265648 0.69
SCHEMBL14436739 0.68 MEN1 (0.35) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116916755-A Materials and methods for extending the shelf life of food products JP实验室公司 2023-10-20 CN claimed
US-4105696-A Asymmetric synthesis of organic compounds HOFFMANN-LA ROCHE INC. (US) 1978-08-08 US claimed
CN-116916755-A Materials and methods for extending the shelf life of food products JP实验室公司 2023-10-20 CN disclosed
US-7262315-B2 For silylation, hydrosilylation, amination, aldol condensations, and cyclization CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2007-08-28 US disclosed
US-7262315-B2 For silylation, hydrosilylation, amination, aldol condensations, and cyclization CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2007-08-28 US disclosed
EP-0710646-B1 1,5-Disubstituted 7a-methylperhydroinden-3a-ol derivatives, active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing them SIGMA TAU IND FARMACEUTI (IT) 1998-12-16 EP disclosed
US-5705531-A CONGESTIVE HEART FAILURE AND HYPERTENSION TREATMENT SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 1998-01-06 US disclosed
EP-0710646-A1 1,5-disubstituted 7a-methylperhydroinden-3a-ol derivatives, active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing them Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) 1996-05-08 EP disclosed
US-4189447-A Substituted-hydroxytetrahydroindanones HOFFMANN-LA ROCHE INC. (US) 1980-02-19 US disclosed
US-4110380-A Asymmetric synthesis of organic compounds HOFFMANN-LA ROCHE INC. (US) 1978-08-29 US disclosed
US-4108898-A Asymmetric synthesis of organic compounds HOFFMANN-LA ROCHE INC. (US) 1978-08-22 US disclosed
US-4105696-A Asymmetric synthesis of organic compounds HOFFMANN-LA ROCHE INC. (US) 1978-08-08 US disclosed
US-4102929-A Asymmetric synthesis of organic compounds HOFFMANN-LA ROCHE INC. (US) 1978-07-25 US disclosed
US-3975440-A Asymmetric synthesis of organic compounds HOFFMANN-LA ROCHE INC. (US) 1976-08-17 US disclosed
US-3975442-A STEROID INTERMEDIATES HOFFMANN-LA ROCHE INC. (US) 1976-08-17 US disclosed