Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30659844 | 0.95 | ITGB3 (0.39) | ITGB3ITGB1ITGAVITGA4TSHR | |
| SCHEMBL12983433 | 0.84 | ITGB3 (0.40) | ITGB3ITGB1ITGAVITGA4TSHR | |
| SCHEMBL1931711 | 0.84 | — | — | |
| SCHEMBL1773442 | 0.74 | — | — | |
| SCHEMBL620598 | 0.74 | — | — | |
| SCHEMBL16488377 | 0.72 | ITGB3 (0.36) | ITGB3ITGB1ITGAVITGA4TSHR | |
| Hydrochloric Acid SCHEMBL7981555 | 0.72 | ITGB3 (0.36) | ITGB3ITGB1ITGAVITGA4TSHR | |
| SCHEMBL1308184 | 0.72 | ITGB3 (0.36) | ITGB3ITGB1ITGAVITGA4TSHR | |
| SCHEMBL30601862 | 0.72 | ITGB3 (0.36) | ITGB3ITGB1ITGAVITGA4TSHR | |
| SCHEMBL12629591 | 0.72 | ITGB3 (0.36) | ITGB3ITGB1ITGAVITGA4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780386-B1 | Matrix metalloprotease inhibitors | HOFFMANN LA ROCHE (CH) | 2002-10-02 | — | — | EP | disclosed |
| US-5932595-A | ANTIARTHRITIC AGENT; MULTIPLE SCLEROSIS; OSTEOPOROSIS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTIULCER AGENT | SYNTEX (U.S.A.) INC. (US) | 1999-08-03 | — | — | US | disclosed |
| EP-0780386-A1 | Matrix metalloprotease inhibitors | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-25 | — | — | EP | disclosed |