Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299181 | 0.98 | ELANE (0.36) | ELANE | |
| SCHEMBL1931297 | 0.94 | ELANE (0.36) | ELANE | |
| SCHEMBL24630147 | 0.90 | ELANE (0.32) | ELANE | |
| SCHEMBL1931528 | 0.90 | ELANE (0.38) | ELANE | |
| Formic Acid SCHEMBL28145465 | 0.89 | ELANE (0.34) | ELANE | |
| SCHEMBL19940867 | 0.83 | ELANE (0.32) | ELANE | |
| SCHEMBL16050853 | 0.82 | ELANE (0.38) | ELANE | |
| SCHEMBL7300563 | 0.81 | USP2 (0.41) | ELANE | |
| SCHEMBL7308268 | 0.81 | ELANE (0.37) | ELANE | |
| SCHEMBL7312356 | 0.79 | ESR2 (0.36) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780386-B1 | Matrix metalloprotease inhibitors | HOFFMANN LA ROCHE (CH) | 2002-10-02 | — | — | EP | disclosed |
| US-5932595-A | ANTIARTHRITIC AGENT; MULTIPLE SCLEROSIS; OSTEOPOROSIS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTIULCER AGENT | SYNTEX (U.S.A.) INC. (US) | 1999-08-03 | — | — | US | disclosed |
| EP-0780386-A1 | Matrix metalloprotease inhibitors | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-25 | — | — | EP | disclosed |