Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1931528 | 0.85 | ELANE (0.38) | ESR2ELANEMAPK1 | |
| SCHEMBL6974068 | 0.83 | HRH3 (0.39) | ESR2ELANEMAPK1ALDH1A1KMT2A | |
| SCHEMBL25647202 | 0.83 | ESR2 (0.35) | ESR2ELANEALDH1A1KMT2A | |
| SCHEMBL6562501 | 0.83 | BTK (0.39) | ESR2ELANEKMT2A | |
| SCHEMBL15628142 | 0.81 | HK2 (0.39) | ESR2ELANECDK9 | |
| SCHEMBL7299181 | 0.81 | ELANE (0.36) | ESR2ELANE | |
| SCHEMBL1931297 | 0.81 | ELANE (0.36) | ESR2ELANE | |
| SCHEMBL22728413 | 0.80 | CTSK (0.35) | ESR2ELANEALDH1A1KMT2AKDM4E | |
| SCHEMBL7308248 | 0.79 | ELANE (0.35) | ELANE | |
| SCHEMBL26964726 | 0.78 | BTK (0.38) | ESR2ELANEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780386-B1 | Matrix metalloprotease inhibitors | HOFFMANN LA ROCHE (CH) | 2002-10-02 | — | — | EP | disclosed |
| US-5932595-A | ANTIARTHRITIC AGENT; MULTIPLE SCLEROSIS; OSTEOPOROSIS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTIULCER AGENT | SYNTEX (U.S.A.) INC. (US) | 1999-08-03 | — | — | US | disclosed |
| EP-0780386-A1 | Matrix metalloprotease inhibitors | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-25 | — | — | EP | disclosed |