Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 19/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299762 | 0.82 | PDE5A (1.00) | PDE5A | |
| SCHEMBL7305647 | 0.81 | PDE5A (0.74) | PDE5A | |
| SCHEMBL2199779 | 0.80 | PDE5A (0.66) | PDE5A | |
| SCHEMBL5231538 | 0.73 | PDE5A (0.57) | PDE5A | |
| SCHEMBL10205334 | 0.72 | GUSB (0.68) | PDE5A | |
| SCHEMBL7305892 | 0.72 | PDE5A (0.77) | PDE5A | |
| SCHEMBL7348770 | 0.72 | PDE5A (1.00) | PDE5A | |
| SCHEMBL29290068 | 0.70 | PDE5A (0.75) | PDE5A | |
| SCHEMBL7309738 | 0.70 | PDE5A (0.85) | PDE5A | |
| SCHEMBL5231531 | 0.69 | PDE7A (0.76) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636626-A1 | Pyrazolopyrimidine Derivatives | LABORATOIRES GLAXO SA (FR) | 1995-02-01 | — | — | EP | disclosed |