Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.51 |
| ▸ | MMP3 | P08254 | 6/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.47 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 4/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299696 | 0.83 | CAPN1 (0.56) | MMP8MMP9CAPN1MMP2 | |
| SCHEMBL7304649 | 0.83 | CAPN1 (0.56) | MMP8MMP9CAPN1MMP2 | |
| SCHEMBL7299705 | 0.83 | CAPN1 (0.56) | MMP8MMP9CAPN1MMP2 | |
| SCHEMBL7304634 | 0.83 | CAPN1 (0.56) | MMP8MMP9CAPN1MMP2 | |
| SCHEMBL7769536 | 0.82 | FNTA (0.57) | MMP8FNTAFNTBEPHX1NAAA | |
| SCHEMBL2750641 | 0.82 | FNTA (0.57) | MMP8FNTAFNTBEPHX1NAAA | |
| SCHEMBL20542992 | 0.81 | EPHX1 (0.63) | MMP8MMP3PLA2G2APLA2G5MMP9 | |
| SCHEMBL20542668 | 0.81 | EPHX1 (0.63) | MMP8MMP3PLA2G2APLA2G5MMP9 | |
| SCHEMBL20542669 | 0.81 | EPHX1 (0.63) | MMP8MMP3PLA2G2APLA2G5MMP9 | |
| SCHEMBL20542990 | 0.81 | EPHX1 (0.63) | MMP8MMP3PLA2G2APLA2G5MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5214056-A | Thiol protease inhibitors | JAPAN TOBACCO INC. (JP) | 1993-05-25 | — | — | US | claimed |
| US-5214056-A | Thiol protease inhibitors | JAPAN TOBACCO INC. (JP) | 1993-05-25 | — | — | US | disclosed |
| EP-0460239-A1 | 1,3,2-DIOXATHIOLANE OXIDE DERIVATIVE | Japan Tobacco Inc. (JP) | 1991-12-11 | — | — | EP | disclosed |