Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 9/20 | 0.56 |
| ▸ | CAPN9 | O14815 | 2/20 | 0.56 |
| ▸ | CTSB | P07858 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ANPEP | P15144 | 1/20 | 0.53 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304634 | 1.00 | CAPN1 (0.56) | CAPN1CAPN9CTSBMAPK1ANPEP | |
| SCHEMBL7304649 | 1.00 | CAPN1 (0.56) | CAPN1CAPN9CTSBMAPK1ANPEP | |
| SCHEMBL7299705 | 1.00 | CAPN1 (0.56) | CAPN1CAPN9CTSBMAPK1ANPEP | |
| SCHEMBL7299741 | 0.84 | NMT2 (0.44) | CAPN1CAPN9CTSBMAPK1ANPEP | |
| SCHEMBL7299733 | 0.84 | NMT2 (0.44) | CAPN1CAPN9CTSBMAPK1ANPEP | |
| SCHEMBL7308362 | 0.83 | MMP8 (0.51) | CAPN1MMP2MMP9MMP8 | |
| SCHEMBL18941372 | 0.82 | CAPN1 (0.62) | CAPN1CAPN9CTSBMAPK1ANPEP | |
| SCHEMBL7306287 | 0.80 | ANPEP (0.64) | ANPEPMMP9MMP8 | |
| SCHEMBL7306277 | 0.80 | ANPEP (0.64) | ANPEPMMP9MMP8 | |
| SCHEMBL7305439 | 0.80 | LAP3 (0.62) | CTSBANPEPDNPEPCTSLMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5214056-A | Thiol protease inhibitors | JAPAN TOBACCO INC. (JP) | 1993-05-25 | — | — | US | claimed |
| US-5214056-A | Thiol protease inhibitors | JAPAN TOBACCO INC. (JP) | 1993-05-25 | — | — | US | disclosed |
| EP-0460239-A1 | 1,3,2-DIOXATHIOLANE OXIDE DERIVATIVE | Japan Tobacco Inc. (JP) | 1991-12-11 | — | — | EP | disclosed |