SCHEMBL7308367

SCHEMBL7308367

CCCCNC(=O)[C@H](C)C[C@H](O)[C@@H](N)C[C@H](Cc1ccc(OC)c(OCc2ccncc2)c1)C(C)C

nearest known ligand 0.98

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.98

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7300793 0.99 REN (1.00) REN
SCHEMBL7307196 0.92 REN (0.98) REN
Hydrochloric Acid SCHEMBL7307108 0.91 REN (1.00) REN
SCHEMBL7304005 0.89 REN (0.98) REN
SCHEMBL7303088 0.88 REN (0.98) REN
Hydrochloric Acid SCHEMBL7311220 0.88 REN (1.00) REN
SCHEMBL7300135 0.87 REN (0.98) REN
SCHEMBL7300340 0.87 REN (0.98) REN
Hydrochloric Acid SCHEMBL7302750 0.87 REN (1.00) REN
SCHEMBL7308671 0.87 REN (0.98) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0678503-B1 Delta-amino-gamma-hydroxy-omega-aryl alkanoic acid amides with enzyme especially renin inhibiting activities NOVARTIS AG (CH) 1999-09-01 EP claimed
EP-0678503-A1 Delta-amino-gamma-hydroxy-omega-aryl alkanoic acid amides with enzyme especially renin inhibiting activities CIBA-GEIGY AG (CH) 1995-10-25 EP claimed