SCHEMBL7308392

SCHEMBL7308392

CCCCc1nc(CO)c(C(=O)OCc2ccc(-c3ccccc3-c3nnn[nH]3)cc2)[nH]1

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 8/20 0.42
AGTR2 P50052 8/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3841156 0.95 AGTR1 (0.44) AGTR1AGTR2
SCHEMBL7308925 0.87 AGTR1 (0.39) AGTR1AGTR2
SCHEMBL3844399 0.87 AGTR1 (0.40) AGTR1AGTR2
SCHEMBL1673090 0.82 AGTR1 (0.43) AGTR1AGTR2
SCHEMBL3841057 0.82 AGTR1 (0.41) AGTR1AGTR2
SCHEMBL7312346 0.80 AGT (0.46) AGTR1AGTR2
SCHEMBL7309889 0.78 AGTR1 (0.41) AGTR1AGTR2
SCHEMBL7304493 0.78 AGTR1 (0.47) AGTR1AGTR2
SCHEMBL7885602 0.78 AGTR1 (0.37) AGTR1AGTR2
SCHEMBL8861121 0.77 AGTR1 (0.38) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0503785-A1 1-Biphenylimidazole derivatives, their preparation and their therapeutic use Sankyo Company Limited (JP) 1992-09-16 EP disclosed