Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | BCL9 | O00512 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MYOC | Q99972 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18412616 | 0.88 | MGLL (0.53) | MGLLGAAALOX5BCL9CTNNB1 | |
| SCHEMBL17373926 | 0.87 | MGLL (0.60) | MGLLGAABCL9CTNNB1ALDH1A1 | |
| SCHEMBL14907652 | 0.85 | MGLL (0.67) | MGLLGAABCL9CTNNB1MAPT | |
| SCHEMBL14907653 | 0.82 | MGLL (0.72) | MGLLGAABCL9CTNNB1ALDH1A1 | |
| SCHEMBL6816134 | 0.82 | MEN1 (0.63) | GAAALOX5ALDH1A1MAPTLMNA | |
| SCHEMBL30685129 | 0.82 | MGLL (0.60) | MGLLGAAALOX5BCL9CTNNB1 | |
| SCHEMBL21069827 | 0.82 | MGLL (0.60) | MGLLGAAALOX5BCL9CTNNB1 | |
| SCHEMBL7068808 | 0.82 | BCL9 (0.56) | MGLLGAABCL9CTNNB1ALDH1A1 | |
| SCHEMBL6900510 | 0.82 | GAA (0.48) | MGLLGAAALOX5BCL9CTNNB1 | |
| SCHEMBL11980594 | 0.82 | MGLL (0.60) | MGLLGAABCL9CTNNB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240000947-A1 | POLYPEPTIDE MODIFICATION AND CONJUGATION METHODS | Encodia, Inc. (US) | 2024-01-04 | — | — | US | disclosed |
| US-10836720-B2 | Inhibitors of integrin alpha 5 beta 1 and methods of use | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-11-17 | — | — | US | disclosed |
| US-20190144386-A1 | INHIBITORS OF INTEGRIN ALPHA 5 BETA 1 AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-05-16 | — | — | US | disclosed |
| EP-0508220-B1 | Derivatives of amindinophenylalanine, procedure for their preparation, their utilisation and compositions comprising them | BEHRINGWERKE AG (DE) | 1995-07-26 | — | — | EP | disclosed |
| US-5274098-A | Amidinophenylalanine derivatives, process for their preparation, their use and compositions containing them | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | disclosed |
| EP-0508220-A1 | Derivatives of amindinophenylalanine, procedure for their preparation, their utilisation and compositions comprising them | BEHRINGWERKE Aktiengesellschaft (DE) | 1992-10-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190144386-A1 | INHIBITORS OF INTEGRIN ALPHA 5 BETA 1 AND METHODS OF USE | ITGA5, ITGB5, ITGB1 | MGLL 4355/4885GAA 1580/4885ALOX5 856/4885 |
| US-10836720-B2 | Inhibitors of integrin alpha 5 beta 1 and methods of use | ITGA5, ITGB5, ITGB1 | MGLL 4355/4885GAA 1580/4885ALOX5 856/4885 |
| US-20240000947-A1 | POLYPEPTIDE MODIFICATION AND CONJUGATION METHODS | PHAX, PTMS, DNPEP | MGLL 4354/4885GAA 970/4885ALOX5 4811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.