Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY1 | Q08828 | 16/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | SCN1A | P35498 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10586330 | 0.93 | ADCY1 (0.57) | ADCY1MAPK1CYP3A4TSHRGMNN | |
| SCHEMBL10585769 | 0.93 | ADCY1 (0.57) | ADCY1MAPK1CYP3A4TSHRGMNN | |
| SCHEMBL10583757 | 0.90 | ADCY1 (0.63) | ADCY1MAPK1CYP3A4TSHRGMNN | |
| SCHEMBL7295262 | 0.89 | ADCY1 (0.61) | ADCY1MAPK1CYP3A4TSHRNR1I2 | |
| SCHEMBL10494966 | 0.89 | ADCY1 (0.58) | ADCY1MAPK1CYP3A4TSHRGMNN | |
| SCHEMBL9737018 | 0.89 | ADCY1 (0.58) | ADCY1MAPK1CYP3A4TSHRGMNN | |
| SCHEMBL10586036 | 0.89 | ADCY1 (0.53) | ADCY1MAPK1CYP3A4TSHRGMNN | |
| SCHEMBL7303938 | 0.88 | ADCY1 (0.54) | ADCY1MAPK1CYP3A4TSHRGMNN | |
| SCHEMBL10584713 | 0.87 | ADCY1 (0.52) | ADCY1MAPK1CYP3A4TSHRGMNN | |
| SCHEMBL7303390 | 0.87 | ADCY1 (0.53) | ADCY1MAPK1CYP3A4TSHRGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447962-A1 | Labdanes and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-25 | — | — | EP | disclosed |
| EP-0315097-A2 | Acyl labdane derivatives, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-05-10 | — | — | EP | disclosed |